Honestly, i used to carry my old D810 in a basic rucksack and ended up with a pinched nerve after a week in Glacier. The D850 is a tank, and adding that 70-200mm glass makes weight distribution critical. For hiking in the PNW, you need a proper suspension system that shifts the load to your hips instead of your spine. Ive been using the MindShift Gear FirstLight 30L Backpack for my heavier kits and it handles the bulk well.

• the torso length is adjustable which helps for a proper fit
• fits the D850 with the 70-200 attached plus your primes easily
• looks like a standard trail pack so it doesnt scream expensive gear The dedicated waist belt is what saves your back on those long uphill stretches. Its a solid, no-nonsense choice that stays comfortable even when its fully loaded with heavy glass.

Try these reliable options:

• Lowepro ProTactic BP 450 AW II: great protection, kinda bulky.
• Peak Design Everyday Backpack 30L V2: discreet, thinner straps. Both handle D850 weight well.

TL;DR: Invest in a mountain-focused pack with an internal modular system from a brand like Shimoda Designs or F-Stop Gear. When youre dealing with a heavy setup like the D850 and a 70-200mm, the harness system is the most important technical detail. A standard rucksack wont have the internal frame needed to transfer that weight to your hips. Look into packs that use removable inserts. This allows you to scale the gear you carry based on the hike. Also, consider the PNW weather. Most modular mountain bags are built with weather-resistant fabrics that handle mist and light rain better than generic bags. They also dont scream camera gear since they look like standard outdoor gear. If those are too pricey, an alternative is buying a quality technical trekking pack and adding a separate padded insert. Its less convenient for quick swaps, but your back will feel the difference. Just make sure the pack has an adjustable torso... makes a huge difference.

Same here!